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Moore (shoulder) is believed to have sustained an AC joint sprain in Thursday's victory over the Lions, and although "it's not a serious injury" he is uncertain for Week 3., Ian Rapoport of NFL Network reports.

Head coach Joe Brady did not provide a postgame update on Moore after he left Thursday's contest in the second quarter, but more details are now available, and it appears Moore is not facing any sort of extended absence. He will have over a week to rest and recover before the Bills square off against the Chargers, and if he's unable to go by then that will mean more snaps for Khalil Shakir, Keon Coleman and Joshua Palmer.

Palmer caught one of three targets for 43 yards with a touchdown in Thursday's 41-31 win over the Lions.

Palmer didn't score at all last season in his first campaign with the Bills, but he's now found the end zone in back-to-back weeks. He's hauled in just one pass in each of the first two games, but he could see more looks if DJ Moore's shoulder injury puts him on the shelf for a stint. Palmer, Khalil Shakir and Keon Coleman would likely work as the main wide receiver trio if Moore can't suit up next week against the Chargers.

Shakir brought in three of six targets for 38 yards and returned one kickoff for 11 yards in the Bills' 41-31 win over the Lions on Thursday.

Shakir played a complementary role once again, and although he did finish tied for second in targets on the Bills, he was only third in receptions and fourth in receiving yards. He's seen Dalton Kincaid take on a much bigger role in the passing game over the first two games of the season, but the wideout is still averaging 6.0 targets over that same span and could be due for a boost in workload if DJ Moore misses any games with the shoulder injury that knocked him out of Thursday's contest late in the second quarter. Shakir will next take aim at the Chargers defense in a Week 3 home matchup on Sunday, Sept. 27.

Coleman brought in all six targets for 63 yards in the Bills' 41-31 win over the Lions on Thursday.

Coleman benefited from the late second-quarter exit of DJ Moore (shoulder), finishing the game second in receptions and receiving yards for the Bills while also tying for runner-up status in targets. The oft-maligned 2024 second-round pick encouragingly flashed steady hands as well throughout the night, and Coleman will be in line to continue in an enhanced role in a Week 3 home matchup against the Chargers on Sunday, Sept. 27 if Moore is forced to sit out the contest.

Williams brought in two of four targets for 33 yards in the Lions' 41-31 loss to the Bills on Thursday.

Williams produced modest numbers for the second time in as many games to open the season, and the speedy wideout didn't even record his second reception until just before the two-minute warning in the second half. Both of Williams' catches Thursday went for first downs, but he saw a sizable reduction from the nine targets he'd logged in the season-opening overtime victory against the Saints on Sunday. The 2022 first-round pick will look to put together his first standout performance of the season in a Week 3 home matchup against the Jets on Sunday, Sept. 27.

LaPorta brought in six of seven targets for 52 yards and a touchdown in the Lions' 41-31 loss to the Bills on Thursday.

The fourth-year tight end was one of Jared Goff's primary targets Thursday, finishing tied for second in receptions while checking in third in both receiving yards and targets. LaPorta also recorded his first touchdown catch of the season on a one-yard grab early in the fourth quarter, and over the first two games of the new campaign, he's encouragingly been targeted 15 times and parlayed those opportunities into 11 receptions for 100 yards and the TD. LaPorta should remain a key complementary option during a Week 3 home matchup against the Jets on Sunday, Sept. 27.

Kincaid brought in seven of eight targets for 95 yards and a touchdown in the Bills' 41-31 win over the Lions on Thursday.

The star tight end put together a fitting encore to his season-opening 5-130-0 line against the Texans, setting the pace for the Bills in receptions, receiving yards and targets on the night. Kincaid repeatedly got into the second level of the Lions defense during the high-scoring victory -- including on his 16-yard scoring grab late in the first half -- and his particularly elevated workload was partly the byproduct of DJ Moore's exit with a shoulder injury shortly before the tight end's touchdown catch. Kincaid will remain a vital component of the Bills' red-hot air attack in a Week 3 home showdown against the Chargers on Sunday, Sept. 27.

Goff completed 26 of 38 passes for 327 yards with four touchdowns and no interceptions while adding three rushes for seven yards in the Lions' 41-31 loss to the Bills on Thursday. He also committed two fumbles, losing one.

Goff's final line undoubtedly pleased fantasy managers, but in a real-world football sense, they were largely the byproduct of a high-scoring loss in which the Lions trailed throughout. He had a mostly unremarkable first half, throwing just one of his touchdown passes in that span when he connected with Jahmyr Gibbs from 11 yards out. Goff would go on to add two and 27-yard strikes to Amon-Ra St. Brown and a one-yard scoring toss to Sam LaPorta after halftime, pushing the veteran signal-caller to a sparkling 6:0 TD:INT over the first two games of the season. Goff will next take aim at the Jets secondary in a Week 3 home matchup on Sunday, Sept. 27.

Bates hit five of his six extra-point attempts in Thursday's 41-31 win over the Lions.

When the kicker missed, Amazon Prime announcer Al Michaels joked that it was the only thing that had gone wrong for Buffalo on the night. To be fair to Bass, he did make field goals from 46, 34 and 33 yards and all three of his extra-point attempts in Week 1. He is also clearly still a fantasy-relevant option as the kicker for a high-flying offense led by Josh Allen and James Cook.

Bates made all four of his extra-point attempts and his only field-goal try in Thursday's 41-31 loss to the Bills.

The field-goal attempt came from 31 yards out. Detroit's season has been up and down so far, but Bates has been steady, making all eight of his extra-point tries and both field-goal attempts through two games. He remains the kicker on a high-scoring offense.