Dallas Cowboys wide receiver CeeDee Lamb has continued to be a major contributor in fantasy football despite losing his quarterback, Dak Prescott (hamstring), in the middle of the season. Lamb has looked solid in six full games with Cooper Rush under center, as the two have connected for 41 completions, 429 yards, and two touchdowns. He ranks as the overall WR11 during that six-game span, and he has found the end zone in each of his last two contests. In Week 16, Lamb will take on the Tampa Bay Buccaneers, whose defensive secondary has been suspect at times in 2024. The Buccaneers have allowed the 13th-fewest fantasy points to slot receivers, as well as the 13th-most fantasy points to receivers who operate out wide. Lamb has played 368 snaps (46.6 percent) from the slot this season, which is the seventh-most in the NFL. Still, he should be able to feast against the Buccaneers, who allowed Los Angeles Chargers slot receiver Ladd McConkey to put up five catches, 58 yards, and one touchdown against them in Week 15. For fantasy purposes, Lamb continues to rank as an intriguing fantasy playmaker in the mid-to-low WR1 range this Sunday.

Miami Dolphins running back De'Von Achane heads into Week 16 with five top 15 running back finishes in a row despite only averaging 36.8 rushing yards per contest. His receiving output and his knack for getting in the endzone have kept him a top-10 fantasy running back. He remains 34 receiving yards behind Alvin Kamara for the league lead by running backs. This week, he gets a matchup against the San Francisco 49ers, who struggle at allowing fantasy points to running backs. They rank 21st in fantasy points and 30th in rushing touchdowns allowed per game. The 23-year-old should look to see plenty of targets with the injuries Miami is dealing with at the receiver position this week. He is a must-start top 10 play and is the RB8 in the RotoBaller weekly rankings.

Arizona Cardinals wide receiver Michael Wilson remains a risky WR3/FLEX play in deeper leagues as he prepares to take on the Carolina Panthers. The 24-year-old has been a beacon of availability this season, playing at least 66 percent of offensive snaps in all 14 games. He has a modest stat line of 41 catches, 482 yards, and four touchdowns so far, ranking 52nd among wide receivers in terms of fantasy points (PPR). He had come on strong with 25.2 fantasy points between Weeks 13 and 14, but he dropped down to just 2.9 points with a pair of catches for nine yards last weekend. This week, Wilson faces the Panthers, who have been mediocre in terms of defending wide receivers. Carolina has allowed the 14th-fewest fantasy points to slot receivers this year, as well as the 12th-most fantasy points to receivers who play out wide. For context, Wilson has taken 212 snaps from the slot (30.6 percent), which is the 34th-most among NFL receivers. Managers can certainly justify starting him in deeper fantasy formats, but we'd advise looking elsewhere for production in leagues with 12 teams or fewer.

Arizona Cardinals tight end Trey McBride is arguably the number one overall tight end play in fantasy football in Week 16 when the Cardinals travel to Carolina to take on the Panthers. McBride is having one of the best seasons we've seen from a tight end in recent memory and, statistically, the best in Arizona in a long time. One statistical category that is lacking is touchdown production. McBride just broke the record for most receptions in a season (89) without a touchdown. Cardinals quarterback Kyler Murray has been vocal about getting McBride into the end zone, and they will have a good opportunity to do so, as the Panthers are allowing the most passing touchdowns in the NFL. It's hard to find a better option at the tight end position than McBride, and he should be started in all league formats.

Miami Dolphins quarterback Tua Tagovailoa (hip) has been removed from the injury report after he was a full participant in practice on Friday. The 26-year-old has been cleared to play against the San Francisco 49ers on Sunday afternoon. Tagovailoa has produced a mixed bag of results this season, completing 73.7 percent of his passes for 2,652 yards, 18 touchdowns, and seven interceptions through 10 games. He turned over the football four times last weekend, but he has fared much better at home, which keeps him on the fantasy radar for Week 16. For context, in six games at Hard Rock Stadium this year, Tagovailoa has 12 touchdowns and just three interceptions and all three of those interceptions came in one game (Week 2 versus Buffalo). Losing Jaylen Waddle (knee) this week does make Tagovailoa's job a little more challenging, but he's still worth deploying as a low-end fantasy QB1 versus San Francisco.

Detroit Lions tight end Sam LaPorta hasn't had the monster season that many were predicting but he has made some strides over the last few weeks. Ahead of Week 16 at the Chicago Bears, LaPorta is looking like a good option at the tight end position. The Iowa product scored two touchdowns in the Thanksgiving matchup between the Lions and Bears in Detroit. The Bears are about middle of the pack against tight ends in fantasy points allowed, so LaPorta looks like a promising threat to score a touchdown in this matchup. In his last four games, LaPorta has seen at least six targets in each game and saw 10 targets against Buffalo last week. An increased role along with his red-zone prowess makes LaPorta a favorable start at the tight end position in the fantasy playoffs.

Atlanta Falcons quarterback Kirk Cousins is expected to be released before his $10 million roster bonus is due on March 17, according to ESPN's Adam Schefter. Cousins signed a hefty four-year, $180 million deal with the Falcons last offseason, but the move hasn't panned out very well for Atlanta. The veteran quarterback has the Falcons at 7-7 and second place in the NFC East. He has completed 66.9 percent of his passes for 3,508 yards, 18 touchdowns, and a career-high 16 interceptions. Cousins was benched for first-round pick Michael Penix Jr. ahead of Week 16, and with the news that he'll be cut loose next March, it's possible that the veteran signal-caller doesn't register another snap in a Falcons jersey. The 36-year-old's proven track record should help him land a job somewhere else, but he won't get nearly as lucrative of a deal. He likely won't be a shoo-in to start with his next team, either.

Detroit Lions wide receiver Jameson Williams has a difficult matchup in Week 16 at the Chicago Bears and makes for a risky play in the fantasy playoffs. The Bears defense allows the second-fewest fantasy points to opposing wide receivers and Williams was held to five catches for 28 yards when the teams played in Detroit in Week 13. The speedy wide receiver has the big-play ability to make one play account for a large chunk of a productive day. Against a good pass defense with other options in the Lions' passing offense like Amon-Ra St. Brown, Tim Patrick, and Sam LaPorta, Williams could be a bit overlooked in this game. Look for other more steady options to fill in the receiver spots for fantasy playoff lineups.

Detroit Lions wide receiver Amon-Ra St. Brown is coming off a monster performance against the Buffalo Bills in Week 15. He faces a tough test in Week 16 at the Chicago Bears but should produce for fantasy managers in the fantasy playoffs. The Bears' defense allows the second-fewest fantasy points to opposing wide receivers this season. Chicago held St. Brown in check in Week 13 in Detroit as the talented receiver hauled in five passes for 73 yards on seven targets. Last week, St. Brown had a season-high 18 targets in the team's loss to Buffalo. The volume will not be as heavy in Week 16 but look for St. Brown to be involved as the team's biggest target in the passing game. If the Lions find success on the ground, they could lean into the rushing attack in this game so the game script could be very different from last week. It doesn't figure to be a huge breakout game for St. Brown for the second week in a row but look for a solid performance in this game.

Detroit Lions running back Craig Reynolds is a popular waiver-wire addition ahead of Week 16 against the Chicago Bears but it might be best to check on his role and usage before plugging him into lineups. With David Montgomery (knee) out, it is natural to think that Reynolds could step into the tandem running back role with Jahmyr Gibbs and produce numbers that could be useful for fantasy. But Gibbs could dominate the backfield and be in line for expanded usage and a more featured role with Reynolds and Sione Vaki giving him rest spells. Reynolds could factor into the Lions game plan but in the fantasy playoffs this week it is risky to take that chance and would be better to trust a more reliable option at the position.