Mahomes completed 29 of 41 pass attempts for 318 yards, one touchdown and one interception while taking six carries for 60 yards and another score in Monday's 31-28 loss to the Jaguars.

The highlight that will make the rounds for Mahomes following Monday's game will unfortunately be the interception he threw at the Jaguars' one-yard line that LB Devin Lloyd returned 99 yards the other way for a touchdown. The Chiefs' signal-caller had a strong fantasy night aside from his blunder in the third quarter, eclipsing the 300-yard mark as a passer for the first time this season. Mahomes also finished as Kansas City's leading rusher while scoring his third touchdown on the ground in five starts, just one shy of his career-best mark of four set back in 2022. The 29-year-old will have to move past Monday's sloppy loss in order to prepare for another primetime showdown Week 6 when the Chiefs host the Lions on Sunday Night Football.

Mahomes completed 25 of 37 passes for 270 yards, four touchdowns and no interceptions in Sunday's 37-20 win over Baltimore. He added four rushes for five yards.

Mahomes turned in a vintage effort, perhaps not coincidentally as the return of Xavier Worthy reinforced his wide receiver corps. Mahomes threw four touchdowns in a regular-season game for the first time since Week 10 of the 2023 season, with all four scores coming in the red zone. He primarily attempted passes in the short areas of the field but still recorded six completions of at least 15 yards. This was Mahomes' first game with multiple touchdowns this season, and it also accounted for his highest yardage total of 2025. If Worthy's shoulder holds up, Mahomes could be in for much improved results as the campaign progresses -- particularly once Rashee Rice (suspension) is eligible to return in Week 7.

Hunt rushed seven times for 49 yards and two touchdowns while catching his only target for eight yards in Monday's 31-28 loss to Jacksonville.

Three of Hunt's seven carries came from five yards or closer to the opponent's goal line, and he punched two of them in successfully to finish as the Chiefs' top fantasy RB in Week 5. Co-starter Isiah Pacheco also received seven carries while seeing two more targets as a receiver, but the latter's lack of use in the red zone proved to be the difference Monday. Hunt now is up to three touchdowns on the year, but he leaves much to be desired as a fantasy asset in games he is held out of the end zone. The 29-year-old checks in as a touchdown-dependent flex option against the Lions on Sunday Night Football in Week 6.

Hunt rushed the ball 13 times for 34 yards in Sunday's 37-20 win over Baltimore. He added one reception on one target for 13 yards.

Hunt had split the rushing workload almost exactly evenly with Isiah Pacheco through the first three games of the season, and while the veteran saw 14 touches compared to Pacheco's nine Sunday, their snap count was nearly even (32 for Hunt to 27 for Pacheco). However, Hunt had a poor day by averaging only 2.6 yards per carry, with a long gain of seven yards. He appears to have the trust of the coaching staff, which could insulate his role, but he has yet to reach 35 rushing yards in a game this season.

Harrison recorded four receptions on five targets for 98 yards in Sunday's 22-21 loss to the Titans.

Harrison got off to a remarkable start to the game, leaping over a pair of defenders for what initially appeared to be a 44-yard touchdown on Arizona's opening drive. He was ruled down at the one after review, though it was still his second catch of at least 40 yards this season. Harrison then recorded gains of 20 and 16 yards on Arizona's next drive, before largely disappearing from the game plan as the Cardinals got very conservative on offense. While the performance was nearly much bigger from a fantasy perspective, Harrison is starting to stack together positive showings after delivering 66 yards and a touchdown in Week 4.

Harrison secured six of 10 targets for 66 yards and a touchdown in the Cardinals' 23-20 loss to the Seahawks on Thursday night.

Harrison finished with a team-high yardage total while checking in second in receptions and targets to Trey McBride. The talented wideout also recorded his first touchdown grab since Week 1 on an impressive 16-yard catch in the left corner of the end zone against Devon Witherspoon with 5:50 remaining in the fourth quarter to narrow what had been a 20-6 deficit. Harrison's catch tally was also a season high, affording the 2024 first-round pick some momentum heading into a favorable Week 5 home matchup against the Titans on Sunday, Oct. 5.

Little made his only field-goal attempt and went 4-for-4 on extra-point tries in Monday's 31-28 win over the Chiefs.

Little made the most of his only field-goal try, connecting on a 52-yarder in the fourth quarter. The kicker has now gone 10-for-12 on field-goal attempts, including 2-for-2 from 50-plus yards, while making all 13 of his PATs over five games this year.

Little made 2-of-3 field goals and both extra-point attempts in Sunday's 26-21 win over the 49ers.

The kicker missed a 47-yard attempt late in the fourth, his second miss in as many weeks. Little did make field goals from 26 and 44 yards. For the year, he's now 9-of-11 on field goals and 9-of-9 on extra points.

Jones completed 20 of 29 passes for 212 yards with two touchdowns and no interceptions and added one rush for two yards in the Colts' 40-6 win over the Raiders on Sunday. He also committed a fumble recovered by Indianapolis.

Jones completed 24 of 33 passes for 262 yards, one touchdown and two interceptions in Sunday's 27-20 loss to the Rams.

Mostert rushed seven times for 22 yards in Sunday's 40-6 loss to the Colts.

Mostert rushed four times for 62 yards and caught his only target for 11 yards in Sunday's 25-24 loss to the Bears. He also returned four kickoffs for 96 yards.

Jeudy recorded two catches on five targets for 15 yards in Sunday's 21-17 loss to the Vikings.

Jeudy brought in three of nine targets for 48 yards in the Browns' 34-10 loss to the Lions on Sunday.

Brown brought in four of eight targets for 48 yards in the Chiefs' 31-28 loss to the Jaguars on Monday night.

Brown recorded three receptions on five targets for 38 yards and a touchdown in Sunday's 37-20 win over the Ravens.