Arizona Cardinals quarterback Kyler Murray went off against the Los Angeles Rams on Sunday, completing 17 of his 21 passes for 266 yards, three touchdowns, and no interceptions. No stranger to the ground game, he also added 59 yards on five carries in the 41-10 victory. Pending the results of Monday Night Football, Murray will finish as the week's QB1. Murray wasted no time in getting Arizona's offense going on Sunday, capping their first drive with a 23-yard touchdown pass to Marvin Harrison Jr. and connecting with the rookie again on the very first play of their second drive for a 60-yard score. A third touchdown pass went to Elijah Higgins in the second quarter, giving Murray more scores than incompletions in the first half. His efforts put the Cardinals so far ahead of the Rams that he was removed with eight minutes left in the fourth quarter, logging the first perfect passer rating by a Cardinals quarterback since Kurt Warner in 2008. In Week 3, Murray will again be in the mix for a top-10 finish when the Cardinals host the Detroit Lions.

Arizona Cardinals head coach Jonathan Gannon said that the knee is not a concern for quarterback Kyler Murray (knee), calling him "all good" for the Week 2 contest against the division-rival Los Angeles Rams. Murray found himself on the Cardinals' Week 2 injury report but has practiced in full all week and is not in any danger of missing this weekend's game. It's surely something to watch moving forward, though, especially for a QB like Murray who relies on his legs often. The 27-year-old was inconsistent in the Week 1 loss to the Buffalo Bills and wasn't on the same page with high-profile rookie receiver Marvin Harrison Jr., connecting with him just once for four yards. Murray finished 21-for-31 passing for 162 yards and a touchdown and also had five carries for 57 yards with a lost fumble. He'll look to bounce back in Week 2, where he'll be a midrange QB1 play for fantasy managers.

Arizona Cardinals quarterback Kyler Murray (knee) was listed on the team's first practice report for Week 2 on Wednesday, but he practiced in full and should be fine to play this Sunday against the division-rival Los Angeles Rams. It's something to watch moving forward, but it shouldn't make fantasy managers hesitant to use the 27-year-old signal-caller as a QB1 in starting lineups this weekend. Murray was inconsistent in the Week 1 loss on the road to the Buffalo Bills, going 21-for-31 for 162 yards and a touchdown. He also had five carries for 57 yards and a lost fumble. Murray connected with rookie first-round receiver Marvin Harrison Jr. just once for four yards. It's nothing to be too concerned about yet, and Murray's rushing abilities at QB give him QB1 upside most weeks. Expect Murray to look Harrison's way a lot more in Week 2.

Carolina Panthers running back Miles Sanders was the leading rusher for this offense during the Week 1 loss to the New Orleans Saints. Being the leading rusher sounds nice, but Sanders only finished with 22 yards on five carries. He served as the second string back to Chuba Hubbard, but neither back got anything going last week. To be fair, it was a blowout and the Panthers needed to abandon the passing game in the second half of the contest. Regardless, neither player has a good outlook heading into the Week 2 matchup against the Las Vegas Chargers. It looks like both backs are going to split the workload, which is bad news for values as a whole. Sanders could be a deep or dynasty stash, but he isn't worth rostering in most fantasy formats.

Carolina Panthers running back Miles Sanders (finger) is not carrying an injury designation into the team's divisional matchup against the New Orleans Saints. While limited in practice earlier in the week, Sanders practiced in full on Thursday and Friday. Although rookie Jonathon Brooks (knee) is on the PUP list and will miss four games, there still isn't a fantasy-worthy role for Sanders on the Panthers. He'll be the direct backup to Chuba Hubbard on a low-powered offense. The former Eagle averaged a career-low 3.3 yards per carry in his first season in Carolina in 2023.

Carolina Panthers running back Miles Sanders (finger) was a full-go in practice on Thursday after he was limited on Wednesday. After being limited in the first official practice of the regular season, Sanders now looks ready to go for the Week 1 regular-season opener this Sunday against the division-rival New Orleans Saints. Even with rookie Jonathon Brooks (knee) missing the first four games of the season while on the Physically Unable to Perform list, Sanders belongs on benches to open the year as the clear backup behind starter Chuba Hubbard in Carolina's backfield. The 27-year-old didn't have much of a chance in the Panthers' atrocious offense in 2023 and averaged a career-low 3.3 yards per carry. He is, at best, an early-season handcuff for Hubbard in deeper fantasy leagues.

Los Angeles Rams rookie running back Blake Corum was more involved during the team's blowout loss to the Cardinals on Sunday afternoon but did little to inspire too much confidence. The Michigan product rushed eight times for 28 yards, which made him the leading rusher in the game for L.A. The 3.5 yards per carry leave something to be desired and he was not targeted in the passing game at all. It should be noted that this game was well out of hand, so Corum's involvement might need to be taken with a grain of salt. But it was a good sign that he got some work in. With Puka Nacua (knee) and Cooper Kupp (ankle) now injured the team could become more of a run-first offense with Kyren Williams and Corum shouldered more of a load. Corum is largely touchdown-dependent as a standalone fantasy option but he could be worth stashing for later in the season.

Los Angeles Rams rookie Blake Corum could end up having some stand-alone value in fantasy aside from being a handcuff for Kyren Williams. But in Week 1, fantasy managers would be wise to see how he is used before putting him in the fantasy lineups in his matchup at Detroit. The Lions had a good run defense last year and Corum will be operating behind a healthy Williams on the depth chart. The Michigan product has the potential to score a touchdown in a short-yardage situation but until his usage is more defined it is best to take a wait-and-see approach with Corum. He has a high upside and could end up being a valuable player to roster in the second half of the season, but there is too much unknown in Week 1.

Philadelphia Eagles wide receiver A.J. Brown (hamstring) did not practice on Wednesday. Brown picked up the injury during practice ahead of the Eagles' Week 2 game against the Atlanta Falcons. He has previously stated that the injury would likely cost him "a couple of weeks". As such, the lack of practice activity comes as no surprise. Unless Brown can ramp up his activity later in the week, it would appear that he is in line to miss his second game in a row. Hopefully, Brown's injury does not drag out too long. He was his usual self in Week 1 on his way to five receptions for 119 yards and a touchdown. Fantasy managers will be eager to get that kind of production back.

Philadelphia Eagles wide receiver A.J. Brown (hamstring) told ESPN's Lisa Salters that he expects to miss a couple of weeks due to the hamstring injury that he suffered in practice last Friday. Brown was ruled out of the Monday night contest against the visiting Atlanta Falcons in Week 2 and could also end up missing the Week 3 showdown in New Orleans against the 2-0 Saints. With Brown out, DeVonta Smith and Jahan Dotson will be Philly's top two receivers, with tight ends Dallas Goedert and Grant Calcaterra also seeing more targets from quarterback Jalen Hurts in the passing game. We'll have a better idea of Brown's status for Week 3 when the Eagles return to practice on Wednesday, but fantasy managers should already be looking for a replacement. Browns is a must-start, high-end WR1 when healthy. He caught five of 10 targets for 119 yards and a TD in the Week 1 win over the Green Bay Packers.

Philadelphia Eagles wide receiver A.J. Brown (hamstring) has been downgraded to out ahead of Monday Night Football versus the Atlanta Falcons. He had already been trending in the wrong direction after missing practice on Saturday, and now we get confirmation that he won't suit up on primetime television. Fantasy managers will appreciate the timing of this announcement as it gives them roughly one hour to find a replacement for Brown in their lineups before the Sunday 1 p.m. games kick off. The Eagles will move forward with DeVonta Smith as their No. 1 receiver on Monday with additional opportunities for Saquon Barkley and Dallas Goedert.Jahan Dotson should get more looks, too, but he's not a dependable option for fantasy lineups in leagues with 14 teams or fewer.

The panic surrounding Arizona Cardinals rookie wide receiver Marvin Harrison Jr.'s debut was stifled by a monster performance in the second week of his NFL career. After logging just one catch for four yards in Week 1, Harrison caught four balls for a team-high 130 yards and two touchdowns on Sunday against the Los Angeles Rams. Harrison's first score came four minutes into the game as he brought in a 23-yard pass while falling out the back of the end zone. His second touchdown came on a 60-yard catch-and-run on the first play of the Cardinals' next drive. In the days following the rookie's unimpressive debut, offensive coordinator Drew Petzing acknowledged the importance of getting the ball to the fourth-overall pick of the 2024 Draft. The team targeted Harrison early and often, with Harrison seeing six of his team-leading eight targets in the first half. Harrison is shaping up to be a strong WR2 candidate when Arizona plays the Detroit Lions in Week 3.

Arizona Cardinals wide receiver Marvin Harrison Jr. had a dud of a debut against the Buffalo Bills in Week 1. The fourth overall pick of the NFL draft had just one catch for four yards and wasn't targeted at all in the second half of that game. While the performance was alarming for fantasy managers who paid up to get the vaunted rookie near his ADP of 15, there is hope for improvement in Week 2. Cardinals offensive coordinator Drew Petzing admitted earlier this week that the team needs to prioritize getting the rookie more involved going forward. Harrison will again line up on the outside against a Rams secondary that allowed 121 receiving yards to Jameson Williams last Sunday. The former Buckeye can be started against the Rams with tempered expectations. He projects as a WR2 in Week 2.

Arizona Cardinals rookie first-round wide receiver Marvin Harrison Jr. saw only three targets and caught one of them for four yards in his NFL debut in the Week 1 loss to the Buffalo Bills. Head coach Jonathan Gannon said that Harrison attracted extra coverage from the Bills defense. "As a quarterback, obviously, you're going through your reads," quarterback Kyler Murray said. "Sometimes the ball goes to him, but that's not my job. I have a sense and a feel for guys when they don't get the ball and when they are getting the ball, but I leave that up to Drew. He tells me, 'Don't worry about that type of stuff. Just keep playing your game and get the ball to where the ball is supposed to go.'" Harrison's quiet day could have been a combination of all those things, and Murray mentioned himself he thinks he and Harrison will eventually get on the same page. Going into Week 2, treat Harrison as a high-end WR2 in fantasy.

New York Jets wide receiver Garrett Wilson has yet to post a ceiling game in 2024, having caught just 10 passes for 117 yards through two games thus far. He will look to make a bigger impact in the box score against the New England Patriots in Week 3's Thursday night game. Wilson could very well break out against a Pats defense that is allowing the seventh-most fantasy points per game through the first two weeks of the season and is fresh off getting shredded by DK Metcalf (10 catches for 129 yards and a touchdown) and Jaxon Smith-Njigba (12-117-0). Wilson is a lock for starting lineups as a low-end WR1 in fantasy heading into Thursday night.

New York Jets wide receiver Garrett Wilson caught four of his six targets for 57 yards in a 24-17 win over the Tennessee Titans in Week 2. Wilson finished second on the team in targets, behind only Breece Hall, while his 57 receiving yards were good enough to lead the team in the close win over Tennessee. Wilson has been steady through the first two weeks of the season but fantasy gamers are still waiting for a dominant performance from their first-round draft pick. He will look to provide that for them in Week 3's Thursday night game against the New England Patriots.

New York Jets wide receiver Garrett Wilson caught six of his 11 targets for 60 yards in a Week 1 loss to the San Francisco 49ers. The veteran wide receiver will look to keep it going in a Week 2 road matchup against the Tennessee Titans. Tennessee struggled to slow fantasy receivers in 2023, allowing the eighth-most fantasy points per game to the position. Wilson paced the Jets in targets in Week 1 and should continue to operate as Aaron Rodgers' first read moving forward. That puts Wilson on the map as a top-10 fantasy receiver heading into Week 2.

Indianapolis Colts wide receiver Josh Downs (ankle) was a full participant in practice on Wednesday. Downs had yet to take the field this season due to the injury. After previously stating that he plans to play in Week 3, Downs' official practice participation suggests that that is true. Downs is a talented young receiver for an offense that is growing together. He recorded 68 receptions for 771 yards and two touchdowns in 2023. Downs is not someone you should start in Week 3 but he is worth a stash if you have space on your bench. Either way, he should substantially help quarterback Anthony Richardson as a short-yardage target.

Indianapolis Colts wide receiver Josh Downs (ankle) said he plans to make his season debut in Week 3 at home at Lucas Oil Stadium this Sunday against the visiting Chicago Bears. Downs suffered a right high-ankle sprain at training camp in August and was forced to miss the first two games of the regular season as a result. However, the 23-year-old was 50-50 to play in the Week 2 loss to the Green Bay Packers at Lambeau Field and could get the green light if he's able to do more in practices this week. The third-round selection last year was set to enter the 2024 season as the No. 2 wideout behind Michael Pittman Jr., so Downs' return will be bad news for anyone that plucked Alec Pierce off the waiver wire recently. Downs, himself, is worth a pickup off the waiver wire now that he's nearing his return. The former Tar Heel caught 68 of 98 targets for 771 yards and two scores in 17 games in his rookie season in 2023.

Indianapolis Colts wide receiver Josh Downs (ankle), who is dealing with a high-ankle sprain and was considered 50-50 to play in Week 2 against the Green Bay Packers, has been ruled out on Sunday as caution prevails. Downs suffered the high-ankle sprain in training camp in August and also was inactive for the season-opening loss to the division-rival Houston Texans. The good news, though, is that he was able to practice in full on Friday, so perhaps he'll be ready to make his season debut in Week 3 against the Chicago Bears. With Downs out again, it makes both Alec Pierce, who went over 100 yards and a touchdown in Week 1, and rookie Adonai Mitchell a little more attractive as flex plays in deeper fantasy leagues at Lambeau Field. But when Downs does make his way back, he could eventually settle into the WR2 role in Indy behind Michael Pittman Jr.

Seattle Seahawks tight end Noah Fant (toe) was a limited participant in practice on Wednesday. Fant played a season-high 81 percent of snaps last Sunday but seems to have come out of Week 2 with a toe issue. Even if it's minor, it will be something worth monitoring as the week progresses and the Seahawks release their official injury designations for their upcoming contest in Miami. Fant's production has been underwhelming this year as he has caught just three of seven targets for 25 yards and zero touchdowns. He can be left on waivers in most fantasy leagues.

Seattle Seahawks tight end Noah Fant (toe) was removed from the team's final injury report on Friday and will suit up for the Week 2 contest versus the New England Patriots. Meanwhile, tight end Pharaoh Brown (foot) has been ruled out. There wasn't much question as to whether Fant would be able to play this weekend, but he shouldn't be in many starting fantasy lineups in the second week of the 2024 season. The 26-year-old played 75 percent of the offensive snaps in the Week 1 win over his former team, the Denver Broncos, but it translated to only two catches on four targets for 11 yards receiving. Although Seattle is running a new offense this year under coordinator Ryan Grubb, not much is expected of Fant after he had career-lows in catches (32), targets (43), receiving yards (414) and touchdowns (zero) in 2023. Fant profiles as a touchdown-dependent, low-end TE2 in fantasy in Week 2.

Seattle Seahawks tight end Noah Fant (toe) has been upgraded to a full participant during Thursday's practice session. This means Fant should be ready to play after getting in a limited practice on Wednesday. It's worth noting that Fant has been dealing with this toe issue throughout the preseason. It could very well come back at him, but for now fantasy managers should expect him out there for the Week 2 matchup against the New England Patriots. Fant was quiet in the season opener with two receptions for 11 yards in the win. The Seahawks have a handful of options on offense, so sometimes Fant gets lost in the shuffle. He'll be on the TE2 radar for this weekend's matchup against the Patriots.

Los Angeles Chargers kicker Cameron Dicker made four kicks in a Week 2 win over the Carolina Panthers. Dicker attempted two field goals, making one from 46 yards out and the other from 42. He attempted three extra points as well, missing one. Dicker tried 35 extra points last season and made all 35, so he got one miss out of the way early this year. He should continue to be a solid and consistent fantasy kicker throughout the season.

Los Angeles Chargers kicker Cameron Dicker has a strong matchup against the Carolina Panthers in Week 2. Coming off a game in which he made all three of his field goals and his only extra point try, Dicker could see even more chances to kick against a team that just gave up 47 points to the New Orleans Saints. Dicker's Week 1 field goals came from 53, 24, and 25 yards out. He doesn't have the strongest leg in the NFL in terms of distance, but he's shown excellent accuracy and was the overall K10 in fantasy last season. He's a top-10 option again for Week 2 lineups.

Los Angeles Chargers kicker Cameron Dicker attempted three field goals and one extra point in a Week 1 win over the Las Vegas Raiders. He made all four of his kicks, scoring 10 of the Chargers 22 points. Dicker started off the season just as he left off the last one: very consistent and reliable. He was a top-10 kicker in fantasy last season and should be right up there again this year.