San Francisco 49ers running back Christian McCaffrey disappointed again during a 20-17 loss to the Seattle Seahawks in Santa Clara on Sunday. The All-Pro out of Stanford took 19 carries for 79 yards rushing and four catches of five targets for 27 yards in the passing game. It's almost shocking to see McCaffrey fail to reach the end zone for the second consecutive game since returning from his long injury absence. McCaffrey only had three such games total last year (16 starts). It's hard to say whether McCaffrey's conditioning, opponents' defensive game-planning, or personnel changes to San Francisco's offense are to blame. The Niners' rushing attack certainly missed George Kittle (hamstring) today and his knack for springing CMC to long runs. McCaffrey's 4.2 yards per carry against a vulnerable Seattle run defense would have ranked as his fourth-lowest single-game average of 2023. At least McCaffrey appeared to stay healthy from start to finish. McCaffrey's next chance comes against the Packers at Lambeau Field in Week 12.

San Francisco 49ers running back Christian McCaffrey will look to get into a better rhythm when the team hosts the Seattle Seahawks in Week 11. McCaffrey's season debut last week against the Bucs was disappointing, ending with 39 yards on 13 carries but adding six receptions on seven targets for 68 yards to save his day in PPR formats. On the bright side, McCaffrey emerged healthy from his first game back since Super Bowl LVIII. The two limited practices he logged on Wednesday and Thursday before practicing in full on Friday can likely be chalked up to load management. It was also positive that McCaffrey only ceded two touches to his backups versus Tampa Bay. CMC is likely to increase his efficiency on the ground while maintaining his involvement in the passing game on Sunday. He's also more likely than not to break the seal on this year's touchdown total. Seattle is allowing the 10th-most fantasy points per game to running backs. Sounds like enough good reasons to put McCaffrey into the overall RB1 spot in Week 11.

San Francisco 49ers running back Christian McCaffrey (Achilles) was limited for the second straight day in practice this week on Thursday. McCaffrey made his 2024 debut in the Week 10 win over the Tampa Bay Buccaneers but will most likely continue to have his workload monitored in practice the rest of the season. In his debut last Sunday, the 28-year-old All-Pro back had 19 touches for 107 scrimmage yards while playing 88 percent of the offensive snaps. We'd expect CMC to be removed from the final Week 11 injury report and be San Fran's lead back in a divisional clash against the Seattle Seahawks. Backups Jordan Mason and Isaac Guerendo had a combined two carries for five yards in McCaffrey's return. McCaffrey will be looking to build on his debut last week and is a must-start in all fantasy lineups.

Los Angeles Rams wide receiver Cooper Kupp finished Sunday's win over the Patriots by amassing six receptions (10 targets) for 106 yards. He also found the end zone twice, bringing his total to four during the 2024-25 campaign. Without question, the wideout has been on a roll, catching 24 passes from Matthew Stafford in the last three games. Of course, Kupp still remains a starting fantasy option in the Week 12, Sunday Night Football matchup with Philadelphia. He just may have a tougher time being as productive against a challenging Eagles defense.

Los Angeles Rams wide receiver Cooper Kupp looks to continue his impressive stretch of games this Sunday against the New England Patriots. Kupp has totaled 23 catches, 235 yards, and one touchdown through three games since returning from injury, giving him 15+ fantasy points (PPR) in all three of those contests. This week, Kupp faces a Patriots defense that has been susceptible to the pass when tested. Of course, the Patriots have trailed for most of this season, so it's common for their opponents to run the ball more than they pass, especially as the clock winds down later in the game. With that said, the Patriots have still been thrown against. The Patriots' defense is allowing the 11th-most receptions and touchdown catches to opposing wide receivers, but the 15th-fewest fantasy points to the position. Even with a modest matchup on tap, Kupp has proven that he is matchup-proof and should be deployed in all leagues. Fantasy managers can trust him as a low-end fantasy WR1 this weekend.

Los Angeles Rams wide receiver Cooper Kupp hauled in all seven of his targets for 80 yards during Monday's Week 10 loss to the Miami Dolphins. He played 90 percent of the offensive snaps but saw his second-lowest target total of the season. Although he was out-produced by Puka Nacua on Monday, both players are dependable options in fantasy football, ranking as fringe WR1 options at the moment. Kupp is averaging 18.4 fantasy points per game (PPR) this season and should be started in all leagues heading into next weekend's clash on the East coast versus the New England Patriots.

Houston Texans wide receiver Tank Dell finished his team's 34-10 victory at Dallas with four catches for 54 yards on seven targets. Interestingly, it was exactly the same stat line as No. 1 receiver Nico Collins, who returned to the lineup following a prolonged absence. Texans quarterback C.J. Stroud completed passes to eight different receivers, but running back Joe Mixon accounted for all three of Houston's offensive touchdowns. Dell and the Texans will look for a breakout day against the Tennessee Titans in Week 12.

Houston Texans wide receiver Tank Dell once again finds himself in boom-or-bust Flex/WR3 territory with the Texans taking on the Dallas Cowboys in Week 11. The 25-year-old receiver ranks a disappointing 40th at his position in PPR formats, though the Houston offense is due a major boost with the return of fellow receiver Nico Collins. Now that wide receiver Stefon Diggs (knee) is out for the year, the Houston offense could again look like it did in 2023 with Collins and Dell powering the passing attack. Even against middling Dallas pass defense, though, fantasy managers will have to weigh the risk of starting a No. 2 receiver on a team in the midst of major pass-protection issues.

Houston Texans wide receiver Tank Dell finished with five catches for 39 yards on Sunday in a 26-23 loss to the Detroit Lions. The second-year receiver was targeted a team-high nine times, but finished fourth on the team in receiving yards. The Houston offense didn't do much of anything in the second half, during which they failed to score as Detroit rallied from a 16-point halftime deficit to win the game. Dell's time as the No. 1 receiver is likely coming to an end, as Nico Collins (hamstring) nears a return, but he should still be firmly involved for the AFC South leaders. Houston takes on Dallas in Week 11.

Las Vegas Raiders wide receiver Tre Tucker still hasn't found the stride he had for a two-game stretch earlier in the season. He caught three of his four targets for 28 yards and ran the ball one time for seven yards. He hasn't been a big factor in the offense yet, and he's clearly taken a back seat to fellow WR Jakobi Meyers and tight end Brock Bowers. He'll likely stick in his role as third fiddle on this offense. Despite being a speedster, he simply hasn't been putting himself in position to make many impactful plays for Las Vegas. Week 12 won't present any easier opportunities for him to achieve this, as he'll face the rival Denver Broncos, who are coming off a blowout win against the Atlanta Falcons. Denver limited a much better offense to just six points in Week 11.

Las Vegas Raiders wide receiver Tre Tucker will do his best to get things into gear against the Miami Dolphins in Week 11. He hasn't scored double-digit PPR fantasy points since Weeks 3-4, where he had a nice duo of fantasy-relevant games. Since then, he's managed just nine receptions and 85 receiving yards despite being targeted 22 times. He's rushed twice for 18 yards in that stretch. After initially seemingly breaking out, he's fallen back to Earth. The departure of former lead WR Davante Adams likely means Tucker has to face better coverage from opposing teams. That could be making it harder for him to succeed. He's not worth rostering in the vast majority of leagues.

Dallas Cowboys head coach Mike McCarthy said after the 34-10 loss to the Houston Texans on Monday night that he regrets not giving quarterback Trey Lance an opportunity to run the offense late in the blowout. "I think the one thing I should have done at the end, and I just didn't do, was put Trey in there. I could've gotten him a series. That's one thing that I would second-guess myself on," McCarthy said. The former third overall pick by the San Francisco 49ers in 2021 has barely played in the NFL but should get more opportunities down the stretch in 2024 in a lost season for the Cowboys with Dak Prescott (hamstring) done for the year. Lance, 24, went 4-for-6 for 21 yards and an interception late in the Week 10 blowout loss to the division-rival Philadelphia Eagles. If Dallas gets spanked again in Week 12 by the Commanders, Lance should get some more action.

Dallas Cowboys quarterback Trey Lance stepped into the game late on Sunday, replacing a struggling Cooper Rush in what turned out to be a 34-6 blowout. The former third-overall pick struggled to get the offense going but did provide a bit more of a pop than Rush. Lance completed 4-of-6 passes for 21 yards and an interception while scrambling three times for 17 yards. Mike McCarthy has not named a starter for next Monday's matchup with Houston, but with how poorly Rush played there is a shot that Lance could draw his first start.

Dallas Cowboys quarterback Trey Lance could be involved in certain packages during Sunday's game against the Philadelphia Eagles, according to ESPN's Adam Schefter. Lance has filled a depth role in Dallas ever since being traded by the 49ers, and even with Dak Prescott (hamstring) mulling season-ending surgery, Prescott still remains the Cowboys' No. 2 quarterback behind Cooper Rush. Even if Lance does see the field versus Philadelphia, he's not expected to have a major role. Fantasy managers can continue to leave him on waivers.

Denver Broncos rookie wide receiver Devaughn Vele quietly had a strong performance in the 38-6 blowout win over the Atlanta Falcons on Sunday in Week 11, although he wasn't on the receiving end of one of rookie quarterback Bo Nix's career-high four touchdown passes. Vele finished with four receptions on five targets for 66 receiving yards. Both his targets and yards were second on the team behind Courtland Sutton. The 26-year-old seventh-rounder out of Utah has had some impressive moments in his first NFL season, and while his 66 yards were his second-highest yardage total of the year, he's also failed to reach 40 yards in five of his seven games. Vele will continue to develop alongside Nix but can't realistically be trusted in starting fantasy lineups as anything more than a boom/bust WR5/flex in deeper leagues.

Denver Broncos rookie wide receiver Devaughn Vele is looking to stay more involved in the Week 11 contest against the visiting Atlanta Falcons on Sunday after catching his first career touchdown pass in the Week 10 loss to the Kansas City Chiefs. Vele's 35 offensive snaps he played last Sunday were the most in his first six NFL games, and he caught all four of his targets for 39 yards and the TD. The 26-year-old seventh-rounder out of Utah is actually third on the Broncos in receiving yards (215) this year behind Courtland Sutton and running back Javonte Williams and he should continue to have a role with Josh Reynolds (finger) on Injured Reserve. The Falcons secondary is inconsistent and vulnerable, too, although the lack of consistent volume for Vele makes him hard to recommend for starting fantasy lineups. He's caught 22 of his 27 targets on the year for 215 yards and one TD.

Denver Broncos rookie wide receiver Devaughn Vele found paydirt for the first time in his NFL career on Sunday in the Week 10 loss to the division-rival Kansas City Chiefs on the road, finishing the contest with four receptions for 39 yards and the touchdown. The 26-year-old seventh-rounder out of Utah caught everything thrown his way on the day, and his four targets were tied for second on the team with Marvin Mims Jr. behind WR1 Courtland Sutton. It was nice to see Vele pick up his first NFL touchdown on the first touchdown of the day in this game, but he has gone over four receptions just once and exceeded 50 receiving yards once in his six games played. Expect quarterback Bo Nix to keep spreading the ball around through the air outside of Sutton, which makes it hard to recommend Vele as a flex option in fantasy, even in much deeper leagues.

Cincinnati Bengals wide receiver Andrei Iosivas caught all three of his targets for a total of 46 receiving yards during Sunday's Week 11 loss to the Los Angeles Chargers. The 25-year-old has taken a clear backseat behind Ja'Marr Chase and Tee Higgins this season, but that didn't stop him from delivering modest production in this week's entertaining Sunday Night Football battle between the Bengals and Chargers. Iosivas is an appealing insurance policy in case Chase or Higgins were to miss time, but for now, he shouldn't be started in fantasy leagues. The Bengals have a Week 12 bye before returning to face the Pittsburgh Steelers in Week 13.

Cincinnati Bengals wide receiver Andrei Iosivas was a more attractive deep-league flex option the last three weeks with Tee Higgins (quadriceps) sidelined, but with Higgins returning for the Sunday night game against the Los Angeles Chargers in Week 11, he'll lose most of his streaming appeal. It's not like Iosivas really made a ton of noise in the three games that Higgins missed anyway, as he combined for three receptions on 11 targets for 39 yards and one touchdown in Weeks 8-10. The 25-year-old was talked up in training camp this summer and already has matched a career-high with four touchdown grabs, but he's had a difficult time standing out otherwise as the No. 3 behind Higgins and Ja'Marr Chase. Iosivas is outside the top 50 at his position through 10 weeks and should be avoided on Sunday night with Higgins returning against a stout Chargers defense.

Cincinnati Bengals wide receiver Andrei Iosivas had only one reception in the Week 9 win over the Raiders. However, it at least resulted in a trip to the end zone. With Tee Higgins (quadriceps) unlikely to suit up on Thursday night versus the Ravens, Ja'Marr Chase should continue to get extra attention from Joe Burrow. Although Iosivas could also benefit, he's hard to trust despite the favorable matchup on the horizon.

Pittsburgh Steelers wide receiver Mike Williams made the most of his limited snaps in Week 10 and will look to get more involved in a divisional showdown with the Baltimore Ravens. Williams, who caught his only target for a 32-yard touchdown in his Steelers debut, is likely to see more playing time now in his second week with the team and could get a few shots downfield from quarterback Russell Wilson. This is certainly a matchup that Williams and teammate George Pickens can exploit as the Ravens have surrendered the most fantasy points per game to wideouts this season. While fantasy managers shouldn't be starting Williams in most redraft formats on Sunday, he has some upside as a DFS play in what projects to be a high-scoring affair.

Pittsburgh Steelers wide receiver Mike Williams came down with his only target, a 32-yard touchdown, in a thrilling Week 10 victory over the Washington Commanders. Williams, who was just dealt to the Steelers earlier this week, played just nine snaps in his debut but was trusted by quarterback Russell Wilson with the game on the line. Wilson threw a perfect deep ball to Williams in the end zone that gave Pittsburgh a 28-27 lead after an extra point with just over two minutes remaining. The 30-year-old wideout should see an uptick in snaps going forward and could be on the fantasy radar at some point this season. He'll be an interesting name on the waiver wire in deeper formats ahead of a Week 11 clash with the Baltimore Ravens.

Pittsburgh Steelers wide receiver Mike Williams is expected to be active against the Washington Commanders on Sunday. Less than one week after being traded from the New York Jets, Williams is slated to make his Steelers debut. The veteran filled a depth role in New York but still managed to offer a solid veteran presence, catching 12 passes for 166 yards along the way. He's off the fantasy radar for the moment but could eventually become a nice deep threat for quarterback Russell Wilson, who will be making his third start of the year in Week 10 versus the Washington Commanders.