Purdy completed 25 of 34 pass attempts for 295 yards, five touchdowns and one interception while taking two carries for 11 yards in Monday's 48-27 rout of the Colts.

Purdy took his game to new heights by throwing five touchdown passes in a game for the first time in his career. The 25-year-old attacked Indianapolis' reeling secondary from the onset, firing three scores to three different receivers on San Francisco's first three possessions Monday. Purdy has been on an absolute heater coming out of the 49ers' bye week, amassing 590 passing yards and eight touchdowns without ever being forced to punt in both starts. The Iowa State Cyclone did lose star TE George Kittle (7-115-1) to an ankle injury in the second half, so Purdy could be missing one of his top weapons against the Bears in Week 17.

Purdy completed 23 of 30 pass attempts for 295 yards and three touchdowns while adding seven carries for 44 yards and a lost fumble in Sunday's 37-24 win over the Titans.

The 49ers' Week 14 bye did Purdy wonders. In addition to allowing the quarterback's body to gain strength after returning from injury just weeks prior, it also afforded the coaching staff an extra week to game plan against an inferior opponent. The end result Sunday was the 25-year-old's finest fantasy outing to date in 2025. Purdy will face a stiffer test on the road against the Colts next Monday, but his fantasy arrow is pointing up for Week 16.

Taylor rushed 16 times for 46 yards and a touchdown and brought in all three targets for 33 yards in the Colts' 48-27 loss to the 49ers on Monday night.

Taylor salvaged his fantasy night with a one-yard touchdown run early in the fourth quarter, which narrowed a 34-20 deficit. The star back otherwise was stonewalled on the ground for the majority of the night, although he made some solid contributions as a receiver. Taylor's rushing yardage total was his second lowest of the season, while his average of 2.9 yards per carry was a new low-water mark. He hasn't eclipsed the 100-yard mark on the ground since his memorable 244-yard performance against the Falcons in Berlin in Week 10, and he'll draw another tough matchup at home against the Jaguars in a Week 17 divisional clash Sunday.

Taylor rushed 25 times for 87 yards while bringing in three of four targets for 14 receiving yards in Sunday's 18-16 loss to Seattle.

Since 44-year-old Philip Rivers wasn't able to be a downfield threat in his first start since 2021, he wasn't able to take the pressure off Taylor and Indianapolis' ground game Sunday. Once the Seahawks realized this, the defense was consistently stacking the box against the Colts' top weapon on offense, resulting in a pedestrian mark of 3.5 yards per carry. Taylor suffered a similar fate against Jacksonville in Week 14 after Daniel Jones (Achilles) left the contest, so it may be tough sledding for the superstar running back going forward without the threat of a deep passing attack. The 26-year-old Taylor will receive a heavy workload to help offset the recent drop in efficiency, and a soft matchup against the 49ers' defense next Monday boosts his prospects for Week 16.

London (knee) had three receptions on eight targets for 27 yards in Sunday's 26-19 win over the Cardinals.

London returned from a four-game absence due to a knee injury and was held in check by Arizona's defense. The star wideout was averaging 6.7 receptions and 90.0 yards in nine active games prior to going down in Week 11, highlighting the stark drop-off in production in Sunday's return. The good news is that London appeared to get through the contest without suffering a setback, potentially setting up a true return to form in Week 17 against the Rams.

London (knee) is active for Sunday's game against the Cardinals, Tori McElhaney of the Falcons' official site reports.

London is putting an end to a four-game absence due to a PCL sprain in his left knee, but his inability to practice in any more than a limited capacity during Week 16 prep suggests he may not be able to handle his normal workload. Nevertheless, he put together three straight 100-yard receiving efforts in his last stretch of play Weeks 9-11, so he likely will resume his status as the Falcons' No. 1 WR, at the very least, for QB Kirk Cousins.

London (knee), who is officially questionable for Sunday's battle against Arizona, is expected to play, Adam Schefter of ESPN reports.

Falcons coach Raheem Morris said Friday that he expects London to suit up Sunday, and that outlook doesn't appear to have changed. If London does play, it will mark his return from a four-game absence. He'd immediately slot back in as Atlanta's No. 1 wideout for QB Kirk Cousins, who was the team's backup quarterback the last time London took part in a game.

Goff completed 34 of 54 passes for 364 yards and three touchdowns with no interceptions in Sunday's 29-24 loss to the Steelers. He added one rush for minus-1 yard.

Goff took to the air a season-high 54 times as the Lions played down by two scores for much of the fourth quarter. He was efficient throughout the contest, and he picked up 199 yards and touchdowns of 27 and four yards across the team's final three drives of the game. While it hasn't led to consistent victories, Goff has topped 300 passing yards in three straight games while also throwing seven touchdowns in that span.

Goff completed 25 of 41 pass attempts for 338 yards and three touchdowns in Sunday's 41-34 loss to the Rams.

Matthew Stafford bested Goff in a battle of quarterbacks who were traded for each other back in 2021. The latter actually finished with the superior fantasy score after Goff set a new season high in passing yards. It was the fourth time this season that the Cal product threw for three touchdowns with no interceptions, resulting in a sparkling 5.8 TD/INT through 14 starts. Goff will look to continue his strong fantasy campaign when the Lions host the Steelers next Sunday.

Butker converted three of four field-goal attempts in the Chiefs' 26-9 loss to the Titans on Sunday.

Butker accounted for all nine of the Chiefs' points in the team's first game without Patrick Mahomes (knee), though QB2 Gardner Minshew also suffered what appeared to be a significant knee injury of his own against Tennessee. Butker's made field goals came from 54, 41 and 27 yards, but he missed a 51-yard kick wide right in the third quarter. It's been a subpar season for Butker, who has missed a total of nine kicks, including five field goals and four extra points.

Butker made both field-goal tries and his only extra-point attempt in Sunday's 16-13 loss to the Chargers.

Butker connected from 27 and 47 yards, respectively. The kicker has missed eight times this season between field goals and extra points, though six of those came in the first six weeks of the season. At the same time, the veteran may be limited moving forward by a struggling offense that no longer has Patrick Mahomes (knee) for the rest of the season.

Dart completed seven of 13 passes for 33 yards, no touchdowns and one interception in Sunday's 16-13 loss to the Vikings. He also rushed twice for seven yards.

Dart completed 20 of 36 passes for 246 yards and two touchdowns with one interception in Sunday's 29-21 loss to the Commanders. He added 63 rushing yards on nine carries.

Singletary rushed 11 times for 47 yards and caught his only target for minus-1 yard in Sunday's 16-13 loss to the Vikings.

Singletary carried the ball five times for 13 yards and caught his only target for one yard in Sunday's 29-21 loss to the Commanders.

Slayton caught one of two targets for eight yards in Sunday's 16-13 loss to Minnesota.

Slayton caught four of 10 targets for 53 yards in Sunday's 29-21 loss to Washington.

Warren brought in three of nine targets for 30 yards in the Colts' 48-27 loss to the 49ers on Monday night.

Warren brought in three of six targets for 19 yards in Sunday's 18-16 loss to Seattle.

Likely was not targeted during Sunday's 28-24 loss to the Patriots.

Likely was not targeted Sunday against the Bengals.