Cook rushed 21 times for 132 yards and two touchdowns while catching his only target for three yards in Sunday's 30-10 win over the Jets.

Cook once again operated as the clear lead back, as Ray Davis and Ty Johnson combined for just 30 scrimmage yards, with most of the backups' opportunities coming after the game was well in hand. Buffalo capitalized on a drive-extending roughing the passer penalty to open the scoring with a one-yard Cook rushing touchdown, and he added a 44-yard touchdown run in the second quarter to extend the lead to 20-0. Cook's versatile skill set allows him to stay heavily involved regardless of game script, and he has three total touchdowns heading into Thursday's Week 3 home game against the 0-2 Dolphins after racking up 18 scrimmage TDs in the 2024 regular season.

Cook (hamstring) doesn't have a designation for Sunday's contest at the Jets.

Cook was limited at Wednesday's practice due to a hamstring issue, but a full walkthrough Thursday and uncapped session Friday has cleared him to handle his typical role as the Bills' No. 1 running back. In a season-opening win against the Ravens, he earned 56 percent of the offensive snaps and turned 18 touches into 102 yards from scrimmage and one rushing TD, while reserve RBs Ray Davis and Ty Johnson combined for four touches for 25 total yards.

Cook (hamstring) was listed as a full participant in Thursday's walk-through.

Cook was limited by a hamstring injury Wednesday, but Thursday's full participation listing suggests he isn't in any danger of sitting out against the Jets in Week 2. In the Bills' season-opening win over Baltimore, Cook turned 18 touches into 102 scrimmage yards and a touchdown while Ray Davis and Ty Johnson combined for 25 yards on four touches.

Purdy (toe/shoulder), who has been ruled out for Sunday's game in New Orleans, is considered unlikely to be available for the 49ers' Week 3 game versus the Cardinals, though his condition has improved over the past week, Adam Schefter of ESPN reports. "We'll see for next week," one source told Schefter, regarding Purdy's status. "Next week will be tight, but he progressed a lot this week."

Purdy (toe) has been ruled out for Sunday's game at New Orleans, Matt Maiocco of NBC Sports Bay Area reports.

Purdy, whom head coach Kyle Shanahan has called a "longshot" to play Sunday against the Saints, could miss 2-to-5 weeks with a turf toe variant, Ian Rapoport of NFL Network reports.

Milroe (coach's decision) is inactive but will serve as the Seahawks' emergency third-string quarterback against the Steelers on Sunday, Brady Henderson of ESPN.com reports.

Milroe rushed once for one yard in Sunday's 17-13 loss to the 49ers.

Golden didn't catch either of his two targets but rushed twice for 15 yards in Thursday's 27-18 win over the Commanders. He also had one punt return for minus-2 yards.

Golden (ankle) doesn't have a designation for Thursday's contest versus the Commanders, Wes Hodkiewicz of the Packers' official site reports.

The Packers listed Golden (ankle) as a full participant for Tuesday's walk-through practice.