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Sampson (knee) was placed on injured reserve Tuesday.

It's unclear exactly how much time Sampson will miss, but his placement on IR means he will miss at least the next four games. Jaleel McLaughlin was brought up from the practice squad to take Sampson's roster spot, and both he an Raheim Sanders will work behind starter Quinshon Judkins.

Johnson rushed eight times for 24 yards in the Chiefs' 31-10 win over the Broncos on Monday night. He added two catches for 44 yards on two targets.

The rookie won the RB2 job behind Kenneth Walker pretty convincingly during training camp and the preseason, and Johnson showed why against Denver, consistently making plays with the ball in his hands. Most of his work came late in the fourth quarter with the game out of hand, but it's evident Johnson is a premier bench stash in fantasy should something happen to Walker.

Cooper (ankle) is "week-to-week," and the hope is he returns "within the next four weeks," Ian Rapoport of NFL Network reports.

Cooper underwent an MRI after spraining his ankle in Sunday's victory over the Titans, and per the report he received "positive news" and could be back at some point in the next month. Isaiah Williams picked up the bulk of the work in Cooper's place in Week 1, and he figures to see extra snaps until the rookie first-round pick is ready to return.

Darnold (glute) is "looking at about a four-week return to play" but could return "a little bit sooner than that," Mike Garafolo of NFL Network reports.

Reports on Darnold's return date have varied, but the latest one indicates he could miss a bit more time than initially anticipated. What's certain is he's dealing with what the Seahawks are calling a "very unique" soft-tissue injury, but one that is expected to lead to a long-term absence. Drew Lock should continue to start at quarterback for however long Darnold remains sidelined.

Worthy secured three of six targets for 18 yards in the Chiefs' 31-10 win over the Broncos on Monday night.

Worthy was on the receiving end of Patrick Mahomes' first completion of the season, which went for nine yards and took the Chiefs down to the Broncos' 26-yard line on an opening drive that culminated in a 15-yard touchdown run by the returning signal-caller. Worthy produced modest gains on his other pair of grabs, but Mahomes recorded just five completions overall to wide receivers in the season-opening victory. Worthy boasts the potential for much better production, and he could have a good opportunity to deliver on that upside in a favorable Week 2 home matchup against the Colts on Sunday night.

Kelce brought in three of five targets for 71 yards in the Chiefs' 31-10 win over the Broncos on Monday night.

Kelce comfortably paced the Chiefs in receiving yards while tying for the team lead in receptions and finishing as the runner-up in targets. The legendary tight end's night would have been unremarkable without his game-long 59-yard catch, which came on a third-down play just before the six-minute mark of the third quarter and brought the ball down to the Broncos' four-yard line. Kelce's chemistry with Patrick Mahomes is unquestioned, and with the prolific quarterback looking to be at close to full health already Monday night, fantasy-friendly performances should continue to be the norm between the two as the season unfolds.

Nix completed 17 of 28 passes for 131 yards with one touchdown and one interception while adding three carries for two yards in the Broncos' 31-10 loss to the Chiefs on Monday night. He also committed three fumbles, losing one and recovering one of the two others that remained with Denver.

Nix's season and night immediately got off on the wrong foot when he threw an ill-advised interception into blanket coverage on the part of rookie cornerback Mansoor Delane (shoulder) on the Broncos' opening drive of 2026, setting up the Chiefs' first touchdown of the night. When Nix wasn't turning the ball over -- he also lost the handle on a late third-quarter sack to give Kansas City possession at the Broncos' 34-yard line -- he was having significant trouble producing any noteworthy gains with his arm, averaging just 4.7 yards per attempt overall. Nix did connect with Evan Engram in the first quarter for a 19-yard scoring strike that answered the Chiefs' first touchdown, but he'll have plenty of room for improvement in a Week 2 home matchup against the Jaguars on Sunday.

Mahomes completed 15 of 27 passes for 184 yards with two touchdowns and one interception while adding seven rushes for 23 yards and another score in the Chiefs' 31-10 win over the Broncos on Monday night. He also recovered two fumbles.

Making good on his long-standing pledge to be available for Monday night's game following last December's season-ending knee injury, Mahomes endured a cold start from a statistical standpoint while completing only two of his first 10 passes. However, the two-time regular-season MVP capped off Kansas City's first drive of the season with a 15-yard touchdown run that allayed any fears about his health, and which he punctuated with a dive into the end zone. Mahomes also picked up the pace through the air after his ragged start, and he ended up connecting with Rashee Rice (13 yards) and Kenneth Walker (two yards) for his pair of scoring tosses. The one major blemish on the veteran signal-caller's night came when he air-mailed a pass into the middle of the field early in the second half that was picked off by Brandon Jones at the Chiefs' 29-yard line and set up a Denver field goal. Now with a solid victory over a talented division rival under his belt, Mahomes and the Chiefs head into a Week 2 home matchup against the Colts on Sunday night with plenty of momentum.

Sutton secured two of five targets for 11 yards in the Broncos' 31-10 loss to the Chiefs on Monday night.

Sutton, along with the rest of the Broncos offense, endured a miserable night, and the veteran receiver tied for the second-fewest receptions and third-fewest yards among Denver pass catchers to record at least one grab. Sutton also was the intended receiver on Bo Nix's early-game interception, making it an all-around throwaway season-opening performance. Sutton's first chance to atone comes in Denver's Week 2 home opener Sunday, which sees a talented Jaguars team come into the Mile High City.

Harvey rushed three times for 18 yards, brought in all four targets for 23 yards and returned four kickoffs for 111 yards in the Broncos' 31-10 loss to the Chiefs on Monday night.

Harvey saw an uptick in opportunities as a pass catcher due to game script, one that saw the Broncos fall behind by a 24-10 margin late in the third quarter. The second-year back also was efficient with his trio of carries, which were five fewer than those logged by lead runner J.K. Dobbins. Harvey should have a chance for more opportunities on the ground in most games this season, including a Week 2 home matchup against the Jaguars on Sunday where Denver's offense will have a higher probability of running a more balanced attack.