Buffalo Bills running back James Cook rushed 11 times for an even 100 yards and one touchdown in the team's 24-21 victory over the New England Patriots. He scored a second time on one of his three receptions. The 25-year-old totaled 26 yards through the air. Cook scored Buffalo's first touchdown on a 46-yard sprint past defenders in the second quarter. In the third quarter, he found paydirt on a four-yard swing pass from Josh Allen. Cook continues to make the most of his touches and will be in the RB1/2 range when the Bills host the New York Jets in Week 17.

Buffalo Bills running back James Cook is a must-start RB1 for this weekend's fantasy football playoffs. The 25-year-old bounced back against Detroit last week (133 yards, two touchdowns) after a disappointing affair two weeks ago in Los Angeles (29 yards). Cook takes his momentum into a home matchup against New England. The Patriots have fielded a below-average rush defense all season. The Bills are favored by 14 points, which could lead to more rushing attempts for Cook and his backfield mates, Ray Davis and Ty Johnson.

Buffalo Bills running back James Cook rushed 14 times for 105 yards and two touchdowns in the team's 48-42 victory over the Detroit Lions. He also added one reception for 28 yards. The Lions have been a stout run defense throughout the season but injuries to their front seven are piling up. Cook's first score came from six yards away in the second quarter. His highlight play was a 41-yard scamper for six early in the third quarter. Buffalo utilized all three of their running backs in the win so it was encouraging for Cook's fantasy managers that he made the most of his touches. He'll be in must-start territory next week against the New England Patriots.

Philadelphia Eagles wide receiver A.J. Brown (knee, rest) was listed as a limited practice participant on Thursday. Brown injured his left knee in practice last Thursday and was spotted wearing a soft brace on it after practice. As long as the 27-year-old can practice again on Friday, though, there's a good chance he'll be removed from the final injury report entirely. Fantasy managers shouldn't really be all that concerned about Brown's knee, but rather quarterback Jalen Hurts' head, as he remains in the concussion protocol and is in danger of missing this weekend's game. Brown's value as a high-end WR1 in fantasy could take a significant hit if backup QB Kenny Pickett (ribs) is forced to make his first start of the year against Dallas. Still, even after Hurts left last Sunday's loss to the division-rival Washington Commanders early, he still finished with eight catches on a season-high 15 targets for 97 yards and a touchdown.

Philadelphia Eagles wide receiver A.J. Brown had a game-high eight grabs for 97 yards in Sunday's loss to the Washington Commanders. He also had a touchdown, pulling in a four-yard throw from Kenny Pickett in the first quarter. Jalen Hurts (concussion) was ruled out early in this one. However, Brown still managed to put together one of his best performances of the 2024-25 campaign. With the 27-year-old finding the end zone in each of his last two games, he remains a must-start against the Cowboys in Week 17, even if Hurts isn't cleared to suit up.

According to Tom Pelissero of the NFL Network, Philadelphia Eagles wide receiver A.J. Brown (knee) is off the injury report and good to go for Sunday's divisional matchup against the Washington Commanders. Brown opened the week as a non-participant and then logged two limited sessions on Thursday and Friday. However, this injury seems rather minor, as Brown is already off the injury report. Last weekend, Brown enjoyed a nice performance, catching eight of his 11 targets for 110 yards and a score. Since Week 6, the top wideout has averaged a solid 15.8 PPR points per game with 82.7 yards per game. With Brown expected to see his typical workload, he should be viewed as a must-start WR1 despite facing a Washington secondary that recently welcomed back Marshon Lattimore.

Detroit Lions tight end Sam LaPorta found the end zone once again against Chicago as the Lions defeated the Bears 34-17 on Sunday afternoon. LaPorta caught four passes for 43 yards and a touchdown. He hauled in a 21-yard touchdown pass on a memorable fake which saw quarterback Jared Goff stumble and running back Jahmyr Gibbs dive on the ground as if the ball had been fumbled. Goff then regained his feet and threw a dart to LaPorta for the touchdown in what appeared to be a planned misdirection. Last game against the Bears in Detroit in Week 13, LaPorta scored two touchdowns and he was able to add another one this week in Chicago.

Detroit Lions tight end Sam LaPorta hasn't had the monster season that many were predicting but he has made some strides over the last few weeks. Ahead of Week 16 at the Chicago Bears, LaPorta is looking like a good option at the tight end position. The Iowa product scored two touchdowns in the Thanksgiving matchup between the Lions and Bears in Detroit. The Bears are about middle of the pack against tight ends in fantasy points allowed, so LaPorta looks like a promising threat to score a touchdown in this matchup. In his last four games, LaPorta has seen at least six targets in each game and saw 10 targets against Buffalo last week. An increased role along with his red-zone prowess makes LaPorta a favorable start at the tight end position in the fantasy playoffs.

Detroit Lions tight end Sam LaPorta saw a season-high 10 targets in Week 15's loss to the Buffalo Bills. LaPorta caught seven passes for 111 yards in the contest but did not find the end zone. It was his first game this season with more than 100 receiving yards and the seven catches were also a season-high. LaPorta had a productive game in this one as the Lions were forced to throw the ball a lot in this game. The versatile tight end was held out of the end zone but had his most productive statistical night of the season. In a thin tight-end landscape for fantasy, LaPorta looks like one of the more reliable options at the position.

Tampa Bay Buccaneers wide receiver Jalen McMillan caught five of his seven targets for 57 yards and one touchdown during Sunday's Week 16 loss to the Dallas Cowboys. The rookie has been a terrific contributor for Tampa Bay this season, filling in admirably as the team's No. 2 wide receiver with Chris Godwin (ankle) done for the year. McMillan has come on particularly strong lately, catching 14 passes for 191 yards and four touchdowns over his last three games. He has found the end zone in three consecutive contests, cementing himself as a very strong WR3/FLEX option moving forward. He should continue to be started in most leagues ahead of next week's matchup against the Carolina Panthers.

Tampa Bay Buccaneers wide receiver Jalen McMillan has come out of nowhere and become a viable fantasy option over the last few weeks. The rookie wideout has nine receptions for 134 yards and three touchdowns over the last two games. Before Week 14, McMillan hadn't surpassed 35 receiving yards in a single game this season. The 13 targets over the last two weeks suggests that the Bucs are going to keep throwing McMillan's way going forward. He'll get a plus-matchup against a banged up Dallas Cowboys defense in Week 16. McMillan has done enough lately to put himself on the flex radar, but he's probably more of a deep league option.

Tampa Bay Buccaneers wide receiver Jalen McMillan has been quiet throughout most of the season until he posted a 59-yard performance last week. At first glance, this outing seemed like a fluke, but McMillan proved that he's a legitimate threat on Sunday. The rookie wideout hauled in five of his six targets for 75 yards and a touchdown in the win over the Los Angeles Chargers. The 23-year-old has come out of nowhere and posted three touchdowns in his last two games. The third-round rookie looks to keep the good times rolling against the Dallas Cowboys next weekend. Fantasy managers should consider McMillan a flex option for that one.

Atlanta Falcons wide receiver Darnell Mooney was the team's leading receiver on Sunday with five receptions for 82 yards but was unable to find the end zone as Bijan Robinson punched in both of Atlanta's offensive touchdowns in the lopsided 34-7 win. Drake London also caught five passes but totaled just 59 yards on his receptions. He also left the game in the fourth quarter with a hamstring injury, although coach Raheem Morris stated after the game that London could have gone back in, however, with a comfortable lead there was no reason for him to reenter. Mooney is nearing his first 1000-yard season since 2021, and can likely still be trusted again next week with the chemistry he showed with Michael Penix Jr., but in the matchup with Washington he is probably a WR3 at best. Managers will want to monitor London's status throughout the week, and if the hamstring injury were to cause him to miss time, then Mooney could be in line for a few more targets.

Atlanta Falcons wide receiver Darnell Mooney picked a terrible time to have his worst outing of the season, recording zero catches on one target against a depleted Raiders defense. The 27-year-old posted a one-catch performance back in Week 1, but averaged almost five catches per contest from Week 2-14. Now, with confidence shaken combined with a rookie quarterback making his first start, fantasy managers who survived Week 15's debacle must decide whether or not to use Mooney in Week 16. The lack of success last week should probably be attributed to Kirk Cousins more than Mooney, however. Still, even though the Falcons are nine-point favorites on Sunday versus the Giants, Atlanta is likely to deploy a heavy dose of Bijan Robinson and Tyler Allgeier against a defense that has yielded the fourth-most fantasy points to running backs on the season. If the Falcons do need to ask Michael Penix Jr. to throw, then the receivers should see some success, as New York allows the third-highest completion rate to QBs and has only intercepted a pass twice on the entire year. All that being said, Mooney looks like a shaky WR3 in the fantasy playoffs this Sunday.

Atlanta Falcons wide receiver Darnell Mooney garnered a single target in Monday's 15-9 win over the Raiders, but failed to haul it in, finishing with zero catches on the night. Mooney had been limited in practice by a foot injury earlier in the week but was cleared to play, so the dud seemed to be more a result of Kirk Cousins lobbing up just 17 passes on the night and completing only 11 of them. It is a punch in the gut for managers who were relying on the wideout in the fantasy playoffs after he'd received six targets in 10 of Atlanta's prior 13 games coming into Monday night and caught at least three passes in 11 of 13. For fantasy managers that were able to survive this showing, the fifth-year pro will be hard to trust in next week's home matchup versus the Giants, especially given how poorly Kirk Cousins looked in Week 15 against a softer pass defense.

Buffalo Bills wide receiver Keon Coleman caught one pass for 17 yards in the team's 24-21 victory over the New England Patriots. The rookie didn't log a reception until early in the second half. He was targeted on a deep pass in the second quarter that landed in the hands of a New England defender. The Buffalo passing offense was out of sync on Sunday. Josh Allen threw for 154 yards. Coleman has four targets in the two games since his return from a wrist injury. It'll be difficult to insert the second-round pick into starting lineups when the Bills face the New York Jets in Week 17.

Buffalo Bills wide receiver Keon Coleman was quiet in all but one play (a 64-yard reception) against the Detroit Lions. Despite his lackluster usage, the rookie was on the field for 63% of the snaps in his first game back from a wrist injury. That was more than any other Buffalo receiver. Coleman may play the most but Buffalo often rotates their receivers and Josh Allen spreads the football around. Khalil Shakir, who mans the slot, is the most reliable of the group. The Bills are favored by 14 points, which could lead to more rushing attempts rather than downfield throws, an area where Coleman shines. The second-round pick is in the WR5 range in the rankings this week.

Buffalo Bills wide receiver Keon Coleman caught one pass for 64 yards in the team's 48-42 win over the Detroit Lions. The rookie only saw two targets in his first game since Week 9. His lone reception came on a deep completion after a Josh Allen scramble drill. Unfortunately, Coleman wasn't more involved, given the 559 offensive yards that Buffalo racked up. Just nine of Allen's 23 completions were to wide receivers as the coaching staff utilized several running backs and tight ends. With how Allen shares the love on offense, Coleman will be difficult to trust in Week 16 against the New England Patriots.

Miami Dolphins wide receiver Malik Washington caught three of four targets for 28 yards in the 29-17, Week 16 win over the San Francisco 49ers. With Jaylen Waddle (knee) sidelined for this game, the rookie could not take advantage of more snaps. The Miami passing attack struggled somewhat and leaned more on the ground game. Waddle could miss more than just this game, making his status something to be monitored throughout this week. Washington will look to bounce back next Sunday when he and Miami hit the road to take on the Cleveland Browns in a game that will possibly be in freezing temperatures.

Miami Dolphins wide receiver Malik Washington may have a chance to have a productive performance in Week 16. Jaylen Waddle (knee) is listed as doubtful, and Tyreek Hill (wrist/personal) is questionable. The rookie had his best performance of the season last week with five receptions on six targets for 52 yards against the Houston Texans. The matchup against the San Francisco 49ers defense will be a difficult one. Their defense is ranked second in fantasy points and second in yards allowed per game to opposing wide receivers. Washington has looked great in special teams and has done whatever is asked of him on the field. He should be viewed as an emergency flex option in Week 16.