Mahomes completed 29 of 45 passes for 276 yards and a touchdown with an interception in Sunday's 22-19 loss to the Broncos. He added three rushing yards on one carry.

Even with Patrick Surtain (pectoral) still sidelined, Mahomes had trouble breaking down the Denver secondary, with his lone TD pass coming in the fourth quarter on a play in which Travis Kelce did most of the work. The star QB did at least extend his streak of games with 250-plus passing yards to seven, a stretch in which he's posted a 15:5 TD:INT, 66.8 percent completion rate and 7.7 YPA. Mahomes will try to get back on track, and revive Kansas City's suddenly fading playoff hopes, at home in Week 12 against the Colts.

Marks rushed for 18 times for 44 yards and brought in his only target for seven yards in the Texans' 16-13 win over the Titans on Sunday.

Marks surprisingly found running room hard to come by against what had been a very generous Titans defense. However, the good news for Marks' fantasy managers was the fact he finally operated as the clear lead option over Nick Chubb, who garnered only three carries. Sunday's results not withstanding, Marks has an encouraging outlook for a Week 12 Thursday night home matchup against the Bills' porous front seven.

Houston offensive coordinator Nick Caley said Wednesday that giving Marks a greater workload in last week's win over Jacksonville was not part of the plan entering the game, Sam Warren of the Houston Chronicle reports.

Marks got into a rhythm early against the Jaguars, and Caley abandoned a plan for backfield balance with Nick Chubb. "You go into a game and you sit there and try to have balance in the variety of ways for all the right reasons," Caley said. "Sometimes, you get into a rhythm. And he played well and he was playing well down the stretch." Marks and Chubb have been co-lead backs since Week 3, but the rookie was given a resounding 80 percent of the offensive snaps last week compared to Chubb's 13 percent. While it looks to the naked eye that Marks has moved ahead of Chubb, Caley is leaving wiggle room by saying "it's hard to say how every game's going to go." It's likely that both backs will get their opportunities going forward, but the slight playing time edge that once favored the veteran Chubb may be leaning Marks' way for the rest of the season.

Marks carried the ball 14 times for 63 yards and a touchdown and caught two of three targets for 18 yards in Sunday's 36-29 win over Jacksonville.

The rookie RB led the Texans' backfield with 16 touches (to Nick Chubb's six) and 81 scrimmage yards to the veteran's 52, and Marks capped his strong performance with a one-yard TD plunge in the second quarter. He's seen double-digit carries in four straight games as he continues to push his way to the top of the depth chart, and Marks could deliver another big performance in Week 11 against the Titans -- a defense he erupted for 119 combined yards and two touchdowns against in Week 4.

Wilson is positioned as the No. 1 wideout for Sunday's game against the Jaguars with Marvin Harrison (appendix) ruled out again, Theo Mackie of The Arizona Republic reports.

Wilson enjoyed a career day with Harrison sidelined during the Cardinals' loss to the 49ers in Week 11, securing 15 of 18 targets for 185 yards with zero touchdowns. While it's unlikely Wilson manages to reprise similarly exuberant target volume from quarterback Jacoby Brissett, who attempted a tremendous 57 passes against San Francisco, double-digit looks wouldn't be out of the question versus Jacksonville. Until such time as Harrison retakes the field, Wilson will continue to benefit from heavy enough involvement to warrant fantasy consideration, especially in PPR formats.

Wilson reeled in 15 of 18 passes for 185 yards and no touchdowns during Sunday's 41-22 defeat to the 49ers.

The Cardinals were quickly in catch-up mode Week 11, with QB Jacoby Brissett eventually attempting 57 passes and completing 47 of them to set a single-game NFL record in the latter category. Wilson was the biggest beneficiary in the absence of No. 1 WR Marvin Harrison (concussion), but it was difficult to project such an outburst from the former, as his previous single-game highs were eight catches, nine targets and 95 receiving yards through two-and-a-half years as a pro. A repeat performance from Wilson is unlikely next Sunday against the Jaguars, but if Harrison remains sidelined, Wilson still should be heavily involved in Arizona's passing attack.

Wilson will take on the No. 1 WR role in the Cardinals offense for at least Sunday's game against the 49ers following Marvin Harrison's appendectomy Monday, Darren Urban of the team's official site reports.

Wilson is in sole possession of third in most receiving categories among Arizona's skill-position players behind TE Trey McBride and Harrison. With Harrison's 6.9 targets per game now up for grabs for the foreseeable future, Wilson stands to benefit along with Greg Dortch, Xavier Weaver (ankle) and Andre Baccellia. Wilson has averaged 10.5 yards per catch and 6.1 yards per target this season, so even with the expected bump in volume he may not produce enough on game days to be a consideration in many fantasy formats.

Nacua caught seven of eight targets for 75 yards and rushed twice for 18 yards in Sunday's 21-19 win over the Seahawks. He also lost a fumble.

Nacua accounted for 75 of Matthew Stafford's 130 passing yards as the Rams' prolific passing offense slowed down Sunday. Davante Adams caught his seventh receiving touchdown in the past four games, but Nacua remains the top overall target for Stafford, who has a 22:0 TD:INT in his last seven starts. Nacua has accrued at least 85 scrimmage yards in seven of nine appearances heading into a Week 12 home game against the Buccaneers on SNF.

Nacua brought in five of six targets for 64 yards and a touchdown in Sunday's 42-26 win over San Francisco.

Nacua showed no ill effects from the minor chest injury he picked up in last week's contest, rewarding managers with his second score in as many appearances. Co-star Davante Adams (oblique) picked up a minor injury at the tail end of the win, but early indications point toward both superstar wideouts being available for next Sunday's NFC West showdown against the Seahawks. Nacua is putting together another strong fantasy campaign, compiling 830 yards from scrimmage and five total touchdowns across the eight games in which he's played.

Nacua (chest) practiced in full Thursday, Adam Grosbard of The Orange County Register reports.

Nacua noted as much and also relayed that his ribs "feel good" after making an early exit from this past Sunday's win against the Saints. Coach Sean McVay told Grosbard on Wednesday that scans of Nacua's ribs came back negative, and after following up a limited showing to begin Week 10 prep with no restrictions one day later, he's in the clear ahead of Sunday's road showdown with the 49ers.

Santos went 4-for-5 on field-goal attempts and made his only PAT in Sunday's 19-17 win over the Vikings.

Santos was a busy man in Week 11, making a 38-yard field goal in the second quarter before later adding makes from 54 and 33 yards in the third. The kicker did miss a 45-yard field-goal try halfway through the fourth quarter, but he made up for it with a game-winning 48-yard field goal as time expired in regulation. Santos has now gone 16-for-20 on field-goal attempts, including 4-for-6 from 50-plus yards, while also making all 21 of his extra-point tries over eight contests this season.

Santos made his lone field-goal attempt and all three of his point-after tries during the Bears' 24-20 win over the Giants on Sunday.

Santos was mostly brought out for PATs during the Bears' Week 10 victory, but he connected on a 22-yard chip shot late in the third quarter to reduce the deficit to 17-10. In the three games since returning from a thigh injury, Santos has gone 6-for-8 on field-goal attempts and 9-for-9 on extra-point tries.

Stafford completed 15 of 28 passes for 130 yards and two touchdowns in Sunday's 21-19 win over the Seahawks.

Stafford completed 24 of 36 pass attempts for 280 yards and four touchdowns while taking three kneeldowns in Sunday's 42-26 win over San Francisco.

White rushed 10 times for 51 yards and brought in two of three targets for 11 yards in the Buccaneers' 44-32 loss to the Bills on Sunday.

White is poised to maintain an expanded role Sunday against the Bills, as Greg Auman of Fox Sports reports that Bucky Irving (foot/shoulder) has been ruled out.

White rushed 10 times for 38 yards and brought in all five targets for 16 yards in the Buccaneers' 28-23 loss to the Patriots on Sunday.

Singletary rushed 16 times for 44 yards and two touchdowns and brought in his only target for three yards in the Giants' 27-20 loss to the Packers on Sunday.

Singletary rushed eight times for 20 yards and caught all three of his targets for 53 yards in Sunday's 24-20 loss to the Bears.

Sutton caught four of eight targets for 59 yards in Sunday's 22-19 win over Kansas City.

Sutton secured three of four targets for 24 yards in the Broncos' 10-7 win over the Raiders on Thursday night.

Musgrave was targeted once and caught one pass for minus-1 yard in Sunday's 27-20 victory over the Giants.

Musgrave brought in all three targets for 23 yards in the Packers' 10-7 loss to the Eagles on Monday night.