McCaffrey rushed 10 times for 23 yards and two touchdowns while catching both of his targets for 43 yards in Sunday's 35-13 win over the Dolphins.

McCaffrey opened the scoring with a one-yard touchdown run in the first quarter and added another one-yard touchdown run in the third quarter. The two-touchdown performance brought McCaffrey's career regular-season touchdown total up to 100. Exactly half of those touchdowns have come with the 49ers, as McCaffrey joins Marshall Faulk and Randy Moss as the only players to score at least 50 touchdowns apiece for multiple teams, per ESPN Insights. McCaffrey should continue to contribute as both a runner and a pass catcher in Week 3 against the Cardinals.

McCaffrey rushed 10 times for 68 yards and brought in five of eight targets for 20 yards during the 49ers' 27-7 Week 1 win over the Rams in Melbourne, Australia.

Coming off a 2025 regular season where he was able to suit up for all 17 games while handling 413 total touches, McCaffrey saw a notable workload reduction to open the new campaign. Rookie third-round pick Kaelon Black actually outpaced McCaffrey by four carries, but it was the latter who edged out his new backfield mate for the team lead in rushing yards. McCaffrey flashed his trademark explosiveness when carrying the ball and should still helm the ground attack on the majority of weeks, although lopsided game scripts in either direction could lead to head coach Kyle Shanahan taking the opportunity to curtail his star running back's volume. McCaffrey will next take aim at what is expected to be a vulnerable Dolphins defense in a Week 2 matchup on Sunday, Sept. 20.

McCaffrey (undisclosed) was not listed on the injury report the 49ers released Tuesday, according to Matt Maiocco of NBC Sports Bay Area.

McCaffrey's status has been a hot topic for nearly a month, particularly after it was reported in mid-August that he was dealing with some sort of "tightness." However, McCaffrey himself said in late August that he always planned to take it easy during training camp, and San Francisco's first injury report of the year confirms he is 100 percent. As such, it seems likely the star running back will fill his regular high-volume role when the 49ers kick off their season against the Rams in Australia.

Waddle brought in eight of 10 targets for 138 yards in the Broncos' 20-13 win over the Jaguars on Sunday.

After a completely non-descript Broncos debut in Week 1, Waddle bounced back with a signature performance in Denver's come-from-behind victory. The veteran wideout led his team in all of receptions, receiving yards and targets by a wide margin, and the highlight of his afternoon was a spectacular 49-yard contested catch early in the second quarter that took the ball down to the Jaguars' one-yard line. The caliber of performance was emblematic of why the Broncos traded for Waddle this offseason, and it may serve as a launchpad for his role in the offense moving forward.

Waddle brought in one of three targets for two yards in the Broncos' 31-10 loss to the Chiefs on Monday night.

Waddle's regular-season Broncos debut was as miserable as his final line suggests, as the prominent offseason addition finished last in receptions and yards among Denver players that recorded at least one catch. One of the two targets Waddle couldn't corral was a key third-down drop early in the third quarter, although he was hardly the only underwhelming component of a pass-catching corps that produced a modest 131 total receiving yards. More productive performances are surely ahead for Waddle and the Broncos' air attack, with the first opportunity for atonement coming in a Week 2 home showdown against the Jaguars on Sunday.

Butker went 4-for-5 on field-goal attempts and made all three of his PATs in Sunday night's 33-30 overtime win against the Colts.

Butker was a busy man versus Indianapolis, making field-goal tries from 46, 28, 31 and 40 yards in the victory, the last of which was a game-winner in overtime. The kicker's lone miss of the day came in the second quarter when he pushed a 51-yard attempt wide left. Through two contests, Butker has looked as good as always, converting five of six field-goal attempts, and he'll look to add his first make from 50-plus yards in Week 3 versus Miami.

Butker connected on his lone field-goal attempt and all four of his extra-point tries during Kansas City's 31-10 win over the Broncos on Monday.

Butker's lone field goal was a 28-yard chip shot late in the third quarter, but most of his work came on PATs and kickoffs in Monday's regular-season opener. The offense under Patrick Mahomes and coordinator Eric Bieniemy looked promising in Week 1, so Butker's scoring ceiling figures to be higher this year than it was in 2025. Kansas City will stay at home for a Week 2 tilt against Indianapolis on Sunday.

Smith completed 27 of 41 passes for 247 yards and one touchdown in Sunday's 20-17 overtime loss to the Packers. He also rushed five times for 17 yards.

Smith completed 19 of 24 passes for 215 yards while rushing six times for seven yards in Sunday's 23-10 win over the Titans.

Jeudy failed to haul in his lone target during the Browns' 23-19 win over the Buccaneers on Sunday.

Jeudy caught two passes (on four targets) for 26 yards during the Browns' 34-10 loss to the Jaguars on Sunday.

Grupe (coach's decision) is inactive for Sunday's game against the Packers.

Grupe (coach's decision) is inactive for Sunday's game against the Titans, Amanda Vogt of the Jets' official site reports.

Jets head coach Aaron Glenn said that Jason Sanders will be elevated from the practice squad for Week 1 and will handle kicking duties over Grupe in Sunday's season opener versus the Titans, Zack Rosenblatt of The Athletic reports.