Mahomes completed 29 of 41 pass attempts for 318 yards, one touchdown and one interception while taking six carries for 60 yards and another score in Monday's 31-28 loss to the Jaguars.

The highlight that will make the rounds for Mahomes following Monday's loss will unfortunately be the interception he threw at the Jaguars' one-yard line that LB Devin Lloyd returned 99 yards the other way for a touchdown. The Chiefs' signal-caller had a strong fantasy night aside from his blunder in the third quarter, eclipsing the 300-yard mark as a passer for the first time this season. Mahomes also finished as Kansas City's leading rusher while scoring his third touchdown on the ground in five starts, just one shy of his career-best mark of four set back in 2022. The 29-year-old will have to move past Monday's sloppy loss in order to prepare for another primetime showdown in Week 6 when the Chiefs host the Lions on Sunday Night Football.

Mahomes completed 25 of 37 passes for 270 yards, four touchdowns and no interceptions in Sunday's 37-20 win over Baltimore. He added four rushes for five yards.

Mahomes turned in a vintage effort, perhaps not coincidentally as the return of Xavier Worthy reinforced his wide receiver corps. Mahomes threw four touchdowns in a regular-season game for the first time since Week 10 of the 2023 season, with all four scores coming in the red zone. He primarily attempted passes in the short areas of the field but still recorded six completions of at least 15 yards. This was Mahomes' first game with multiple touchdowns this season, and it also accounted for his highest yardage total of 2025. If Worthy's shoulder holds up, Mahomes could be in for much improved results as the campaign progresses -- particularly once Rashee Rice (suspension) is eligible to return in Week 7.

Cook rushed the ball 15 times for 49 yards in Sunday's 23-20 loss to the Patriots. He did not catch his only target.

Cook endured his worst game of the season both as a rusher and receiver. His longest rush of the day went for only nine yards, and he also went without a catch for the first time on the campaign. Positively, Cook still dominated opportunity out of Bills' backfield, with Ray Davis and Ty Johnson combining to see only four rushing attempts with zero targets. Cook should have a strong chance of bouncing back in Week 6 against Atlanta.

Cook rushed 22 times for 117 yards and a touchdown while bringing in three of four targets for 18 yards in the Bills' 31-19 win over the Saints on Sunday.

The Bills arguably underperformed most of the afternoon given their status as significant home favorites, but Cook's play didn't disappoint. The speedy back was over the 100-yard mark on the ground for the third straight game, and he extended his season-opening streak of rushing touchdowns to four games with a one-yard scoring run late in the first quarter. Cook is averaging 5.4 yards per carry overall, even when factoring in an average of 3.4 yards per tote Week 1 against the Ravens. The versatile fourth-year pro also has multiple catches in three of the first four games heading into a Week 5 AFC East home showdown against the Patriots next Sunday night.

Engram secured four of six targets for 33 yards and a touchdown in the Broncos' 21-17 win over the Eagles on Sunday.

Engram finished second in receptions and targets on an afternoon when Bo Nix spread the ball around to nine different pass catchers overall. The veteran tight end also scored his first touchdown in a Broncos uniform on an 11-yard catch just before the halfway point of the fourth quarter, and his receiving yardage total was a new season high. Engram has played a more short-area role than may have initially been expected upon his signing with Denver this offseason, but his upside keeps him a viable consideration at what can be a difficult position for reliable fantasy production.

Engram (back) practiced fully Friday.

A back issue prevented Engram from practicing and playing in Week 3, but following full practices both Thursday and Friday, the tight end is poised to return to action Monday night against the Bengals. With just four catches (on six targets) for 33 yards in his first two games with the Broncos, the early returns on Engram aren't great, but assuming his back injury is no longer an issue, he's a player capable of picking up the pace, as soon as Monday. With that in mind, Zac Stevens of TheDNVR.com relays that Engram indicated Friday that he feels "great" ahead of Week 4 action, while, for his part, offensive coordinator Joe Lombardi told Stevens that he believes Engram will "be getting going here real soon."

Engram (back) participated in Thursday's practice, Parker Gabriel of the Denver Post reports.

Engram missed practice all last week before ultimately being ruled out for Week 3 against the Chargers. With his return to practice Thursday, Engram should be on track to play Monday night against the Bengals. Engram has massively underwhelmed to start his Broncos career, playing just 38 percent of the offensive snaps across the first two games of the season and catching only four passes for 33 yards on six targets. He's simply not a full-time player in coach Sean Payton's offense that likes to use multiple tight ends and wide receivers.

Taylor rushed 17 times for 66 yards and three touchdowns and brought in three of four targets for 20 yards in the Colts' 40-6 win over the Raiders on Sunday. He also recovered a fumble.

Taylor rushed the ball 17 times for 76 yards in Sunday's 27-20 loss to the Rams. He added five receptions on five targets for 20 yards.

Pickens caught two of four targets for 57 yards and a touchdown in Sunday's 37-22 win over the Jets.

Pickens finished with eight receptions on 11 targets for 134 yards and a pair of touchdowns in Sunday's 40-40 overtime tie against the Packers.

Olave caught seven of 11 targets for 59 yards in Sunday's 26-14 win over the Giants.

Olave hauled in three of six targets for 20 yards and one touchdown during Sunday's 31-19 defeat versus the Bills.